SCHEMBL14799787

SCHEMBL14799787

CC(C)Cn1nc2c(-c3ccc(OC(C)C)cc3)ccc(-c3ccc(OC(C)C)cc3)c2n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.39
▸ MAP4K4 O95819 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ BTK Q06187 1/20 0.37
▸ PRMT3 O60678 2/20 0.36
▸ CARM1 Q86X55 2/20 0.36
▸ PRMT6 Q96LA8 2/20 0.36
▸ PRMT1 Q99873 2/20 0.36
▸ PRMT8 Q9NR22 2/20 0.36
▸ TOP2A P11388 1/20 0.36
▸ NOTUM Q6P988 1/20 0.36
▸ WDR5 P61964 1/20 0.36
▸ MCL1 Q07820 3/20 0.36
▸ BCL2 P10415 1/20 0.36
▸ MDM2 Q00987 1/20 0.36
▸ ALDH1A3 P47895 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ ACACB O00763 1/20 0.34
▸ ACACA Q13085 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799791 0.83 KDM4E (0.44) KMT2ATP53MAPTMCL1MDM2
SCHEMBL19106983 0.80 TOP2A (0.40) KMT2AMAPTTOP2A
SCHEMBL16402077 0.79 MEN1 (0.39) KMT2AMAPTTOP2AMCL1MDM2
SCHEMBL18040334 0.78 TRPV1 (0.45) TOP2A
SCHEMBL16144710 0.76 KIF11 (0.38) TP53TOP2A
SCHEMBL14799769 0.73 TRPV1 (0.39) MAPTTOP2A
Diphenylamine SCHEMBL14799771 0.71 HSD17B10 (0.44) TOP2A
SCHEMBL28527296 0.71 MEN1 (0.42) KMT2ATP53MAPTMCL1MDM2
SCHEMBL17694122 0.70 SLC6A4 (0.33) TOP2A
SCHEMBL29171168 0.70 GRM2 (0.33) TP53TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190284471-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES CHOSHU INDUSTRY CO., LTD. (JP) 2019-09-19 — — US disclosed
US-20180138346-A1 Solar Energy Collection Systems Utilizing Holographic Optical Elements Useful for Building Integrated Photovoltaics NITTO DENKO CORPORATION (JP) 2018-05-17 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 — — US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 — — US disclosed
US-20150041042-A1 PRESSURE SENSITIVE ADHESIVE TYPE OF WAVELENGTH CONVERSION TAPE FOR ENHANCING SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2015-02-12 — — US disclosed
US-20150041042-A1 PRESSURE SENSITIVE ADHESIVE TYPE OF WAVELENGTH CONVERSION TAPE FOR ENHANCING SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2015-02-12 — — US disclosed
US-20150041042-A1 PRESSURE SENSITIVE ADHESIVE TYPE OF WAVELENGTH CONVERSION TAPE FOR ENHANCING SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2015-02-12 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138346-A1 Solar Energy Collection Systems Utilizing Holographic Optical Elements Useful for Building Integrated Photovoltaics CRY1, CRY2, AXIN2 KMT2A 2581/4885MAP4K4 1596/4885TP53 4081/4885
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 KMT2A 645/4885MAP4K4 4444/4885TP53 2203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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