SCHEMBL1480165

SCHEMBL1480165

Cc1ccc(-c2cc3c(cc2C(C)(C)C)-c2cc(C(C)(C)C)c(-c4ccc(C)cc4C)cc2C3)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.37
MAPT P10636 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 2/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
NPC1 O15118 1/20 0.31
TP53 P04637 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACHE P22303 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480576 0.91 TSHR (0.34) METAP1MAPTMEN1KMT2ARAB9A
SCHEMBL1480179 0.84 PGR (0.38) METAP1MAPTRAB9APOLBNPC1
SCHEMBL1480667 0.81 GABRA1 (0.35) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL4954208 0.79 ESR1 (0.36) METAP1MAPTALDH1A1POLBSMN1; SMN2
SCHEMBL1479894 0.77 PGR (0.34) METAP1MAPTRAB9AALDH1A1NPC1
SCHEMBL1480253 0.77 ELANE (0.46) METAP1MAPTMEN1KMT2AGAA
SCHEMBL1480864 0.74 ALDH1A1 (0.41) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL312890 0.74 CYP1A2 (0.34) MAPTALDH1A1KDM4EPOLBSMN1; SMN2
SCHEMBL29545829 0.74 CYP1A2 (0.34) MAPTALDH1A1KDM4EPOLBSMN1; SMN2
SCHEMBL29332473 0.73 METAP1 (0.53) METAP1MAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed