SCHEMBL1480179

SCHEMBL1480179

Cc1cc(Cl)ccc1-c1cc2c(cc1C(C)(C)C)-c1cc(C(C)(C)C)c(-c3ccc(Cl)cc3C)cc1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.38
NOTUM Q6P988 2/20 0.36
METAP1 P53582 1/20 0.35
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
MAPT P10636 2/20 0.33
CASP3 P42574 1/20 0.32
GRM2 Q14416 1/20 0.32
POLB P06746 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ITGA1 P56199 1/20 0.31
HSP90AB1 P08238 1/20 0.31
CYP3A4 P08684 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
HSD17B1 P14061 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1479894 0.92 PGR (0.34) PGRNOTUMMETAP1MAPTCASP3
SCHEMBL1480165 0.84 METAP1 (0.37) METAP1MAPTPOLBNPC1RAB9A
SCHEMBL1479983 0.79 TDP2 (0.37) PGRMETAP1MAPT
SCHEMBL1480667 0.79 GABRA1 (0.35) PGRMAPTCASP3NPC1RAB9A
SCHEMBL1482936 0.78 S100A4 (0.43) NOTUMMETAP1CASP3GRM2NPC1
SCHEMBL1480576 0.77 TSHR (0.34) METAP1MAPTCASP3NPC1RAB9A
SCHEMBL29719717 0.73 NOTUM (0.53) NOTUMCASP3GRM2POLBCYP3A4
SCHEMBL1480864 0.72 ALDH1A1 (0.41) PGRMAPTCASP3NPC1RAB9A
SCHEMBL1480367 0.72 NPC1 (0.51) NOTUMCASP3NPC1RAB9AITGA1
SCHEMBL29545829 0.72 CYP1A2 (0.34) MAPTPOLBCYP3A4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed