SCHEMBL1480667

SCHEMBL1480667

Cc1ccccc1-c1cc2c(cc1C(C)(C)C)-c1cc(C(C)(C)C)c(-c3ccccc3C)cc1C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
GRIA1 P42261 1/20 0.35
CACNG8 Q8WXS5 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
MAPT P10636 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PGR P06401 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
ADORA1 P30542 1/20 0.33
DHFR P00374 1/20 0.33
HTR7 P34969 1/20 0.33
PLA2G7 Q13093 2/20 0.32
AR P10275 1/20 0.32
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480864 0.91 ALDH1A1 (0.41) GABRA1GABRB2GRIA1CACNG8CD274
SCHEMBL16411546 0.83
SCHEMBL27960860 0.82
SCHEMBL1480165 0.81 METAP1 (0.37) MAPTNPC1RAB9ASMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL27960861 0.81
SCHEMBL1480179 0.79 PGR (0.38) MAPTNPC1RAB9APGRPDK2
SCHEMBL1481477 0.79 CYP2D6 (0.37) GABRA1GABRB2MAPTNPC1RAB9A
SCHEMBL312383 0.79 BACE1 (0.34) MAPTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL16411547 0.77 GABRA1 (0.36) GABRA1GABRB2MAPTNPC1RAB9A
SCHEMBL1479792 0.76 NPC1 (0.47) MAPTNPC1RAB9ASMN1; SMN2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed