Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921921 | 0.86 | ALDH1A1 (0.57) | DNM1ALDH1A1CYP3A4ALOX15RECQL | |
| SCHEMBL306231 | 0.86 | ALDH1A1 (0.57) | DNM1ALDH1A1CYP3A4ALOX15RECQL | |
| SCHEMBL316679 | 0.83 | — | — | |
| SCHEMBL1921278 | 0.78 | ESR1 (0.65) | DNM1ALDH1A1CYP3A4ALOX15RECQL | |
| SCHEMBL585745 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15RECQLTHRB | |
| SCHEMBL92754 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15RECQLTHRB | |
| SCHEMBL3371479 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15RECQLTHRB | |
| SCHEMBL3369514 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15RECQLTHRB | |
| SCHEMBL1079767 | 0.74 | ACHE (0.68) | DNM1ALDH1A1CYP3A4ALOX15RECQL | |
| SCHEMBL6051320 | 0.74 | ALDH1A1 (0.68) | DNM1ALDH1A1CYP3A4ALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664238-B2 | Indenoisoquinolinone derivatives, manufacturing method and medical use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2014-03-04 | — | — | US | disclosed |
| US-20130085140-A1 | INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085140-A1 | INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF | MYLK, PTGIS, PGF | DNM1 3249/4885ALDH1A1 1355/4885CYP3A4 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.