Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21061043 | 0.98 | TSHR (0.34) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL16439901 | 0.83 | — | — | |
| SCHEMBL1636885 | 0.77 | ALDH1A1 (0.37) | TSHRALDH1A1KIF11GAAMAPT | |
| SCHEMBL146433 | 0.74 | PDE2A (0.37) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL149760 | 0.74 | TSHR (0.37) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL1079312 | 0.74 | PDE2A (0.34) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL28474116 | 0.74 | ALOX15 (0.34) | TSHRALDH1A1 | |
| SCHEMBL4852287 | 0.73 | TSHR (0.45) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL3081819 | 0.73 | MGLL (0.41) | TSHRMAPK1PTPN5NOS3NOS2 | |
| SCHEMBL9725680 | 0.73 | TSHR (0.35) | TSHRMAPK1ALDH1A1PTPN5NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206683-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | The Board of Trustees of the Leland Stanford Junior University (US) | 2017-08-23 | — | — | EP | claimed |
| WO-2016061538-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR ANESTHESIA | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-21 | — | — | WO | claimed |
| EP-2532663-B1 | Naphthalenetetracarboxylic acid derivatives and their use as semiconductors | BASF SE (DE) | 2016-03-16 | — | — | EP | claimed |
| EP-2532663-A1 | Naphthalenecarboxylic acid derivatives and their use as semiconductors | BASF SE (DE) | 2012-12-12 | — | — | EP | claimed |
| US-8217055-B2 | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-10 | — | — | US | claimed |
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |
| EP-1937672-B1 | N-[(4,5-DIPHENYLPYRIMIDIN-2-YL)METHYL]AMINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2009-09-02 | — | — | EP | claimed |
| US-7541361-B2 | N-[4,5-diphenylpyrimidin-2-yl)methyl]amine derivatives, the preparation thereof and their therapeutic use | SANOFI-AVENTIS (FR) | 2009-06-02 | — | — | US | claimed |
| CN-101400653-A | 11-beta HSD1 inhibitors | WYETH CORP (US) | 2009-04-01 | — | — | CN | claimed |
| EP-1981848-A2 | 11-BETA HSD1 INHIBITORS | Wyeth (US) | 2008-10-22 | — | — | EP | claimed |
| US-5914335-A | INSECTICIDES | RHONE-POULENC INC. (US) | 1999-06-22 | — | — | US | claimed |
| WO-1998028279-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | claimed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | claimed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | claimed |
| US-5556873-A | AGRICULTURAL PESTICIDES | RHONE-POULENC INC. (US) | 1996-09-17 | — | — | US | claimed |
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | claimed |
| US-5177100-A | Pesticides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-05 | — | — | US | claimed |
| EP-0295117-A1 | Derivatives of N-phenylpyrazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-12-14 | — | — | EP | claimed |