Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296691 | 0.85 | KIF11 (0.39) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL16439867 | 0.85 | — | — | |
| SCHEMBL11272457 | 0.85 | KIF11 (0.39) | TSHRALDH1A1KIF11 | |
| SCHEMBL6989320 | 0.78 | KDM1A (0.46) | TSHRMAPK1ALDH1A1KIF11HTR2C | |
| SCHEMBL146433 | 0.76 | PDE2A (0.37) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL262756 | 0.76 | NT5E (0.30) | — | |
| SCHEMBL7682757 | 0.74 | PYCR1 (0.30) | — | |
| SCHEMBL5463356 | 0.74 | TSHR (0.40) | TSHRMAPK1ALDH1A1KIF11 | |
| SCHEMBL696976 | 0.74 | — | — | |
| SCHEMBL457652 | 0.74 | KIF11 (0.32) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-10-10 | — | — | US | claimed |
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-08-17 | — | — | US | claimed |
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | UNIVERSITY OF ROCHESTER (US) | 2023-04-25 | — | — | US | claimed |
| US-20230059662-A1 | Rhenium(V) Alkylidyne Complexes and Methods of Use and Preparation Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-02-23 | — | — | US | claimed |
| EP-3988560-A1 | SMALL-MOLECULE COMPOUND HAVING A2A ADENOSINE RECEPTOR ANTAGONISM | Academy Of Military Medical Sciences (CN) | 2022-04-27 | — | — | EP | claimed |
| WO-2021238328-A1 | COMPOUND CONTAINING HYDROXAMIC ACID, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2021-12-02 | — | — | WO | claimed |
| US-11150555-B2 | Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same | LG CHEM, LTD. (KR) | 2021-10-19 | — | — | US | claimed |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. | 2020-09-15 | — | — | US | claimed |
| US-20200277270-A1 | MICHELIOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | UNIVERSITY OF ROCHESTER | 2020-09-03 | — | — | US | claimed |
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | claimed |
| US-5859272-A | METALLOCENES; PRODUCES POLYOLEFINS HAVING A HIGH MELTING POINT AND A HIGH MOLECULAR WEIGHT; HIGH POLYMERIZATION ACTIVITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-12 | — | — | US | claimed |
| US-5859029-A | TREATING SUBSTANCE P-DEPENDENT PATHOLOGICAL CONDITIONS | SANOFI (FR) | 1999-01-12 | — | — | US | claimed |
| US-5767278-A | ANTICARCINOGENIC AGENTS | GERON CORPORATION (US) | 1998-06-16 | — | — | US | claimed |
| US-5656639-A | POSSESS STRONG AFFINITY FOR NK1 RECEPTORS; USEFUL IN TREATMENT OF SUBSTANCE P-DEPENDENT PATHOLOGICAL CONDITIONS | SANOFI (FR) | 1997-08-12 | — | — | US | claimed |
| US-5616663-A | TRANSITION METAL COMPOUND, ALUMINOXANE, COMPOUND WHICH REACTS WITH TRANSITION METAL COMPOUND TO FORM ION PAIR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | claimed |
| EP-0723959-A1 | Heterocyclic compounds as tachykinin receptor antagonists, process for their preparation and pharmaceuticals containing them | SANOFI (FR) | 1996-07-31 | — | — | EP | claimed |
| US-5492917-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE, ANTIISCHEMIC,ANTISHOCK, ANTIINFLAMMATORY, ANTIALLERGEN AGENTS | MERCK & CO., INC. (US) | 1996-02-20 | — | — | US | claimed |
| WO-1995008989-A1 | ENDOTHELIN ANTAGONISTS INCORPORATING A CYCLOBUTANE | MERCK & CO., INC. (US) | 1995-04-06 | — | — | WO | claimed |
| WO-1994005276-A1 | CYTOTOXIC COMPOUNDS | MORGAN LEE R (US) | 1994-03-17 | — | — | WO | claimed |
| US-5231105-A | Ethylamine derivatives and antihypertensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-07-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230059662-A1 | Rhenium(V) Alkylidyne Complexes and Methods of Use and Preparation Thereof | RNF168, CCND2, RAD50 | TSHR 4514/4885MAPK1 4615/4885ALDH1A1 2336/4885 |
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | TNF, C9, CYP51A1 | TSHR 4837/4885MAPK1 1566/4885ALDH1A1 1456/4885 |
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | RNF168, CCND2, RAD50 | TSHR 4514/4885MAPK1 4615/4885ALDH1A1 2336/4885 |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | TSHR 2846/4885MAPK1 1991/4885ALDH1A1 994/4885 |
| US-20200277270-A1 | MICHELIOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | TNF, C9, CYP51A1 | TSHR 4837/4885MAPK1 1566/4885ALDH1A1 1456/4885 |
| US-11150555-B2 | Photoacid generator and chemically amplified positive-type photoresist composition for thick film comprising the same | ASIC1, PPA1, ATP6AP1 | TSHR 3936/4885MAPK1 1373/4885ALDH1A1 3269/4885 |
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | SI, SCD, SMPD1 | TSHR 4095/4885MAPK1 1890/4885ALDH1A1 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.