Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681116 | 0.77 | ALDH1A1 (0.37) | TSHRALDH1A1HPGDHSD17B10KIF11 | |
| SCHEMBL146433 | 0.74 | PDE2A (0.37) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL149760 | 0.74 | TSHR (0.37) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL101521 | 0.73 | PDE2A (0.36) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL95846 | 0.73 | KIF11 (0.36) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL146946 | 0.73 | TSHR (0.35) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL4852287 | 0.73 | TSHR (0.45) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL148163 | 0.73 | TSHR (0.35) | TSHRMAPK1ALDH1A1PTPN5NOS3 | |
| SCHEMBL3081819 | 0.73 | MGLL (0.41) | TSHRMAPK1PTPN5NOS3NOS2 | |
| SCHEMBL21061043 | 0.71 | TSHR (0.34) | TSHRMAPK1ALDH1A1PTPN5NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148308-A1 | PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-28 | — | — | US | disclosed |
| EP-2865266-A1 | PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS | Sumitomo Chemical Company, Limited (JP) | 2015-04-29 | — | — | EP | disclosed |
| US-5095032-A | PARASITICIDAL NEW SUBSTITUTED THIENOPYRANONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0336186-A2 | Derivatives of triazolylmethylcyclopropyl-carbinols as material protecting agents | BAYER AG (DE) | 1989-10-11 | — | — | EP | disclosed |
| US-4698333-A | Use of substituted malonic acid derivatives as agents for combating pests | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| EP-0081142-B1 | 1,3,5-TRIAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1986-06-25 | — | — | EP | disclosed |
| EP-0118833-B1 | SUBSTITUTED DIAMIDES OF PHENYLHYDROXY-THIOMALONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-04-02 | — | — | EP | disclosed |
| US-4562185-A | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |
| US-4556649-A | Substituted malonic acid diamide insecticides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |
| EP-0148499-A2 | Substituted derivatives of malonic acid, process for their preparation and their use as pesticides | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |
| US-4512797-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| EP-0075117-B1 | 2H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | disclosed |
| EP-0126235-A1 | Five-membered nitrogen-containing heterocycles, process for their preparation and their use as pesticides | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0118833-A1 | Substituted diamides of phenylhydroxy-thiomalonic acids, process for their preparation and their use as pesticides | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0108351-A2 | Use of substituted malonic-acid derivatives as pesticides | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |
| US-4428766-A | 2N-1,2,4,6,Thiatriazine-1,1-dioxides and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0081142-A2 | 1,3,5-Triazinones, process for their preparation and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1983-06-15 | — | — | EP | disclosed |
| EP-0075117-A2 | 2H-1,2,4,6-thiatriazine-1,1-dioxides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| US-4343648-A | 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148308-A1 | PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS | SFXN1, OSR1, PIR | TSHR 3545/4885MAPK1 2945/4885ALDH1A1 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.