Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454389 | 0.83 | ACHE (0.40) | ALDH1A1ACHEAGXTSMN1; SMN2TDP1 | |
| SCHEMBL5566891 | 0.82 | ACHE (0.43) | ALDH1A1ACHEAGXTSMN1; SMN2TDP1 | |
| SCHEMBL12793109 | 0.82 | PTPN1 (0.42) | ALDH1A1ACHETUBB1CYP3A4 | |
| SCHEMBL1635426 | 0.81 | ACHE (0.50) | ALDH1A1ACHEPOLBTDP1TUBB1 | |
| SCHEMBL13338225 | 0.81 | ACHE (0.39) | ALDH1A1ACHEAGXTPOLBRAB9A | |
| SCHEMBL12326160 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ACHEAGXTPOLBRAB9A | |
| SCHEMBL29793476 | 0.81 | ACHE (0.50) | ALDH1A1ACHEPOLBTDP1TUBB1 | |
| SCHEMBL8254929 | 0.79 | ACHE (0.46) | ALDH1A1ACHESMN1; SMN2TDP1TUBB1 | |
| SCHEMBL14458264 | 0.79 | ACHE (0.54) | ALDH1A1ACHEPOLBTDP1TUBB1 | |
| Iodide SCHEMBL8935417 | 0.79 | ACHE (0.48) | ALDH1A1ACHEPOLBTDP1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426115-B2 | Patterning process and resist composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-23 | — | — | US | claimed |
| US-20110033803-A1 | PATTERNING PROCESS AND RESIST COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-02-10 | — | — | US | claimed |
| US-20100159392-A1 | PATTERNING PROCESS AND RESIST COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-06-24 | — | — | US | claimed |
| WO-2019071428-A1 | COMPOUND, PHOTOPOLYMERIZATION INITIATOR, PHOTOCURABLE COMPOSITION AND CURED PRODUCT THEREOF, AND PHOTOCURABLE INK AND PRINT USING THE SAME | DIC CORPORATION (JP) | 2019-04-18 | — | — | WO | disclosed |
| US-20180208579-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-07-26 | — | — | US | disclosed |
| US-10028377-B2 | Resin composition, prepreg and metal foil-clad laminate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20180193341-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-07-12 | — | — | US | disclosed |
| US-9925188-B2 | DNA-PK inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-03-27 | — | — | US | disclosed |
| US-9878993-B2 | DNA-PK inhibitors for treatment of cancer | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-01-30 | — | — | US | disclosed |
| US-20170258789-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-09-14 | — | — | US | disclosed |
| US-9743515-B2 | Resin composition, prepreg and metal-foil-clad laminate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20070265423-A1 | Bifunctional phenylene ether oligomer, its derivatives, its use and process for the production thereof | AMAGAI AKIKAZU | 2007-11-15 | — | — | US | disclosed |
| US-20070232730-A1 | Polyphenylene ether oligomer sulfonic acid salt, making method, flame retardant resin composition, and molded article | SHIN-ETSU CHEMICAL CO., LTD. | 2007-10-04 | — | — | US | disclosed |
| US-7276563-B2 | Polyphenylene ether oligomer compound, derivatives thereof and use thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-7247682-B2 | Bifunctional phenylene ether oligomer, its derivatives, its use and process for the production thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247682-B2 | Bifunctional phenylene ether oligomer, its derivatives, its use and process for the production thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-20070129502-A1 | Polyphenylene ethers; improved chemical resistance, dielectric, low water-absorption, heat resistance, flame retardance, and mechanical properties; laminates | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
| US-7193030-B2 | Acid anhydride and polyimide using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7192651-B2 | Resin composition and prepreg for laminate and metal-clad laminate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7193019-B2 | Process for the production of vinyl compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265423-A1 | Bifunctional phenylene ether oligomer, its derivatives, its use and process for the production thereof | DUOX2, DUOX1, PAOX | ALDH1A1 2332/4885ACHE 1707/4885AGXT 917/4885 |
| US-20170258789-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | ALDH1A1 2935/4885ACHE 4363/4885AGXT 1950/4885 |
| US-20180193341-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | ALDH1A1 2935/4885ACHE 4363/4885AGXT 1950/4885 |
| US-20180208579-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | ALDH1A1 2935/4885ACHE 4363/4885AGXT 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.