SCHEMBL1482676

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3832830	0.91	RAB9A (0.47)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL1496889	0.89	NPC1 (0.56)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL1482531	0.86	RXRB (0.56)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL2474631	0.80	HDAC1 (0.50)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL3835157	0.79	GAA (0.51)	KMT2AMAPTRAB9ALMNAGAA
	SCHEMBL12051789	0.79	NPC1 (0.48)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL1482679	0.78	UTS2R (0.50)	KMT2AMEN1MAPTRAB9ANPC1
	SCHEMBL3835627	0.76	RXRB (0.52)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL3836379	0.75	HDAC1 (0.50)	KMT2AMEN1MAPTL3MBTL1RAB9A
	SCHEMBL1482523	0.75	RAB9A (0.44)	KMT2AMEN1MAPTL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.