Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144727 | 0.92 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL14827747 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL12333943 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL4200884 | 0.84 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL15037990 | 0.82 | NOS3 (0.47) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL7647403 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL12334299 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL4005243 | 0.79 | NOS3 (0.46) | ALDH1A1KDM4ELMNAMAPTPTK2B | |
| SCHEMBL2267570 | 0.79 | HTR2A (0.45) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL14827759 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130081213-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | L'OREAL (FR) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130081213-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | AADAT, TYR, DDC | ALDH1A1 388/4885KDM4E 1899/4885LMNA 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.