Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679951 | 0.81 | L3MBTL1 (0.35) | — | |
| SCHEMBL10728455 | 0.79 | ALDH1A1 (0.39) | — | |
| SCHEMBL11348878 | 0.70 | ALDH1A1 (0.40) | TRPV4 | |
| SCHEMBL27933853 | 0.69 | L3MBTL1 (0.33) | — | |
| SCHEMBL30039434 | 0.67 | ALDH1A1 (0.44) | TRPV4 | |
| SCHEMBL2930464 | 0.67 | ALDH1A1 (0.44) | TRPV4 | |
| SCHEMBL1969747 | 0.66 | — | — | |
| SCHEMBL3835239 | 0.65 | L3MBTL1 (0.33) | — | |
| SCHEMBL691798 | 0.65 | KMT2A (0.45) | TRPV4 | |
| SCHEMBL6208919 | 0.65 | TRPV4 (0.37) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760443-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE IN THE MODULATION RETINOID - RELATED ORPHAN RECEPTOR | Glaxo Group Limited (GB) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013045431-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE IN THE MODULATION RETINOID - RELATED ORPHAN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2013-04-04 | — | — | WO | disclosed |