Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DCK | P27707 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271445 | 0.86 | KDM4E (0.48) | RAB9AKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9702829 | 0.84 | RAB9A (0.51) | RAB9AKDM4EQPCTLQPCTSMN1; SMN2 | |
| SCHEMBL9704789 | 0.84 | RAB9A (0.47) | RAB9AKDM4EQPCTLQPCTSMN1; SMN2 | |
| SCHEMBL9704064 | 0.81 | RAB9A (0.49) | RAB9AKDM4EQPCTLQPCTSMN1; SMN2 | |
| SCHEMBL9702907 | 0.80 | ALDH1A1 (0.57) | RAB9AKDM4EQPCTLSMN1; SMN2KMT2A | |
| SCHEMBL10058752 | 0.79 | QPCTL (0.40) | RAB9AKDM4EQPCTLQPCTSMN1; SMN2 | |
| SCHEMBL9702474 | 0.79 | RAB9A (0.63) | RAB9AKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9702773 | 0.79 | RAB9A (0.66) | RAB9AKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25416550 | 0.79 | HDAC1 (0.40) | RAB9AKDM4EQPCTLQPCTSMN1; SMN2 | |
| SCHEMBL10058947 | 0.79 | RAB9A (0.61) | RAB9AKDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760833-A1 | PYRIDINE DERIVATIVES | Endo Pharmaceuticals Inc. (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013049559-A1 | PYRIDINE DERIVATIVES | ENDO PHARMACEUTICALS INC. (US) | 2013-04-04 | — | — | WO | disclosed |