Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435145 | 0.80 | THRB (0.55) | THRBLMNA | |
| SCHEMBL30801866 | 0.78 | POLB (0.44) | KMT2ASMN1; SMN2SIGMAR1DDB1CRBN | |
| SCHEMBL4555734 | 0.78 | THRB (0.60) | THRBLMNA | |
| Hydrochloric Acid SCHEMBL3602648 | 0.77 | SIGMAR1 (0.43) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL30337582 | 0.77 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2SIGMAR1THRBL3MBTL1 | |
| SCHEMBL1352150 | 0.77 | HTR2C (0.40) | HTR2AHTR2CHTR2BCYP2D6CYP2C9 | |
| SCHEMBL29516262 | 0.73 | SIGMAR1 (0.47) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL30337246 | 0.73 | ENPP2 (0.47) | KMT2ASMN1; SMN2THRBL3MBTL1CYP2D6 | |
| SCHEMBL14833436 | 0.72 | KDM4E (0.61) | KMT2ASMN1; SMN2THRBL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL3602646 | 0.72 | SIGMAR1 (0.46) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |