Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8708050 | 0.94 | EPHX2 (0.40) | S1PR2S1PR1S1PR3TP53DNM1 | |
| SCHEMBL1487731 | 0.92 | S1PR2 (0.40) | S1PR2S1PR1S1PR3TP53DNM1 | |
| Ammonia Solution, Strong SCHEMBL1483368 | 0.85 | TP53 (0.41) | TP53DNM1LPAR1LPAR3SMPD1 | |
| SCHEMBL11504910 | 0.85 | TP53 (0.44) | S1PR2S1PR1S1PR3TP53SMPD1 | |
| SCHEMBL11784357 | 0.82 | TP53 (0.41) | TP53DNM1LPAR1LPAR3SMPD1 | |
| SCHEMBL26634936 | 0.82 | TP53 (0.44) | S1PR2S1PR1S1PR3TP53DNM1 | |
| SCHEMBL8357190 | 0.81 | S1PR2 (0.43) | S1PR2S1PR1S1PR3TP53SMPD1 | |
| SCHEMBL10886731 | 0.81 | S1PR2 (0.43) | S1PR2S1PR1S1PR3TP53SMPD1 | |
| SCHEMBL27220623 | 0.80 | DNM1 (0.50) | DNM1LPAR1LPAR3SMPD1 | |
| SCHEMBL11504958 | 0.80 | S1PR2 (0.42) | S1PR2S1PR1S1PR3TP53SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110175-B2 | Compositions with permeation enhancers for drug delivery | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-09-07 | — | — | US | disclosed |
| US-20200138710-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-05-07 | — | — | US | disclosed |
| US-8822410-B2 | Tympanic membrane permeating ear drops and uses thereof | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-09-02 | — | — | US | disclosed |
| US-20110166060-A1 | TYMPANIC MEMBRANE PERMEATING EAR DROPS AND USES THEREOF | MASSACHUSETTES INSTITUTE OF TECHNOLOGY (US) | 2011-07-07 | — | — | US | disclosed |
| EP-2337544-A2 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | Living Proof, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20110076261-A1 | Antifungal Drug Delivery System | PRUGEN IP HOLDINGS, INC | 2011-03-31 | — | — | US | disclosed |
| WO-2009142719-A2 | TYMPANIC MEMBRANE PERMEATING EAR DROPS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. | 2009-03-12 | — | — | US | disclosed |
| US-20080317737-A1 | Drug combination for the treatment of skin disorders | PRUGEN, INC. | 2008-12-25 | — | — | US | disclosed |
| WO-2008134712-A2 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| US-4906459-A | Hair care compositions | THE PROCTER & GAMBLE COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4902499-A | Hair care compositions containing a rigid silicone polymer | THE PROCTER & GAMBLE COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4842850-A | SHAMPOO | THE PROCTER & GAMBLE COMPANY (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0313307-A1 | Hair care compositions | THE PROCTER & GAMBLE COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4788006-A | Shampoo compositions containing nonvolatile silicone and xanthan gum | THE PROCTER & GAMBLE COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0240350-A2 | Hair care compositions | THE PROCTER & GAMBLE COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| US-4292035-A | COMPLEX OF SMECTITE CLAYS, AMINES, AND ORGANIC SULFONIUM, PHOSPHONIUM, OR QUATERNARY AMMONIUM COMPOUNDS, WITH AN ANIONIC SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4174291-A | DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4062647-A | Clay-containing fabric softening detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4051046-A | ANTISTATIC AGENTS, SOFTENERS, WRINKLE RESISTANCE | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | MMP1, MMP9, MMP17 | S1PR2 4784/4885S1PR1 4537/4885S1PR3 4715/4885 |
| US-11110175-B2 | Compositions with permeation enhancers for drug delivery | ABCB11, MMP1, SLC47A1 | S1PR2 3590/4885S1PR1 3110/4885S1PR3 3229/4885 |
| US-20200138710-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | ABCB11, CFTR, MMP1 | S1PR2 3762/4885S1PR1 3135/4885S1PR3 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.