Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | PKLR | P30613 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337601 | 0.83 | OPRD1 (0.36) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31691821 | 0.81 | HTR1A (0.38) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL443155 | 0.78 | CYP11B2 (0.42) | OPRD1OPRK1POLB | |
| SCHEMBL30149275 | 0.78 | CYP11B2 (0.42) | OPRD1OPRK1POLB | |
| SCHEMBL1813909 | 0.77 | HTR1A (0.42) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL30206827 | 0.77 | HTR1A (0.42) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL444439 | 0.77 | ALDH1A1 (0.36) | OPRM1OPRL1OPRD1OPRK1PKLR | |
| SCHEMBL15401125 | 0.74 | USP30 (0.40) | OPRD1OPRK1POLB | |
| SCHEMBL1600282 | 0.73 | HTR1A (0.34) | HTR1AHTR2AHTR7 | |
| SCHEMBL23530317 | 0.73 | CYP11B2 (0.45) | OPRD1OPRK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576539-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011147765-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | WO | disclosed |