Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.58 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720250 | 0.81 | MAPK1 (0.46) | IMPDH2IMPDH1MEN1KMT2AMAPT | |
| SCHEMBL17667979 | 0.78 | IMPDH2 (0.60) | IMPDH2IMPDH1APPATMMEN1 | |
| SCHEMBL3760031 | 0.78 | IMPDH2 (0.60) | IMPDH2IMPDH1ATMMEN1KMT2A | |
| SCHEMBL17506602 | 0.77 | IMPDH2 (0.69) | IMPDH2IMPDH1APPATMMEN1 | |
| SCHEMBL26912467 | 0.76 | MAPT (0.53) | IMPDH2IMPDH1KMT2AMAPTALDH1A1 | |
| SCHEMBL8161503 | 0.76 | IMPDH2 (0.56) | IMPDH2IMPDH1APPATMMEN1 | |
| SCHEMBL17540776 | 0.74 | IMPDH2 (0.55) | IMPDH2IMPDH1ATMMEN1KMT2A | |
| SCHEMBL5797502 | 0.74 | IMPDH2 (0.55) | IMPDH2IMPDH1ATMMEN1KMT2A | |
| SCHEMBL19454372 | 0.74 | IMPDH2 (0.50) | IMPDH2IMPDH1ATMMEN1KMT2A | |
| SCHEMBL1752696 | 0.74 | IMPDH2 (0.64) | IMPDH2IMPDH1APPATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701429-B2 | Targeted drug delivery through affinity based linkers | Akamara Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| CN-113121402-B | Method for preparing 3-alkynyl indole compound by using gold complex | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113121402-A | Method for preparing 3-alkynyl indole compound by using gold complex | 上海应用技术大学 | 2021-07-16 | — | — | CN | disclosed |
| EP-2575898-B1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND | LIFE MOLECULAR IMAGING SA (CH) | 2020-09-30 | — | — | EP | disclosed |
| US-20200297854-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-09-24 | — | — | US | disclosed |
| US-20200199249-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | Akamara Therapeutics, Inc. (US) | 2020-06-25 | — | — | US | disclosed |
| US-10533059-B2 | Targeted drug delivery through affinity based linkers | Akamara Therapeutics, Inc. (US) | 2020-01-14 | — | — | US | disclosed |
| US-20180120325-A1 | Sequence Specific Fluorescence for Peptide-Fluorochrome Interactions | MedChem Imaging (US) | 2018-05-03 | — | — | US | disclosed |
| EP-3129065-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | Invictus Oncology Pvt. Ltd. (IN) | 2017-02-15 | — | — | EP | disclosed |
| US-20170014528-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2017-01-19 | — | — | US | disclosed |
| US-9409927-B2 | Super lewis acidic borate esters as 18F-labeled PET probes | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150361110-A1 | SUPER LEWIS ACIDIC BORATE ESTERS AS 18F-LABELED PET PROBES | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2015-12-17 | — | — | US | disclosed |
| WO-2015148126-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2015-10-01 | — | — | WO | disclosed |
| US-20150147276-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-05-28 | — | — | US | disclosed |
| EP-2858630-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | President and Fellows of Harvard College (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013185032-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-12 | — | — | WO | disclosed |
| US-20130217920-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2013-08-22 | — | — | US | disclosed |
| EP-2575898-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND | Piramal Imaging SA (CH) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011151282-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014528-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | ABCG2, ADAM8, TIE1 | IMPDH2 2726/4885IMPDH1 2799/4885APP 673/4885 |
| US-11701429-B2 | Targeted drug delivery through affinity based linkers | ABCG2, FCGR2A, ABCB1 | IMPDH2 1082/4885IMPDH1 1393/4885APP 2234/4885 |
| US-20150361110-A1 | SUPER LEWIS ACIDIC BORATE ESTERS AS 18F-LABELED PET PROBES | SLCO2A1, SLCO2B1, FFAR1 | IMPDH2 4115/4885IMPDH1 3774/4885APP 4740/4885 |
| US-20130217920-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | APP, APBA1, BACE1 | IMPDH2 3526/4885IMPDH1 3747/4885APP 1/4885 |
| US-20200199249-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | ABCG2, FCGR2A, ABCB1 | IMPDH2 1082/4885IMPDH1 1393/4885APP 2234/4885 |
| US-10533059-B2 | Targeted drug delivery through affinity based linkers | ABCG2, ADAM8, TIE1 | IMPDH2 2726/4885IMPDH1 2799/4885APP 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.