Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17667979 | 0.76 | IMPDH2 (0.60) | IMPDH2IMPDH1MAPK1ATMGPR84 | |
| SCHEMBL3760031 | 0.76 | IMPDH2 (0.60) | IMPDH2IMPDH1ATMGPR84CYP3A4 | |
| SCHEMBL3769477 | 0.75 | IMPDH2 (0.64) | IMPDH2IMPDH1ATMGPR84CYP3A4 | |
| SCHEMBL17506602 | 0.74 | IMPDH2 (0.69) | IMPDH2IMPDH1ATMGPR84CYP3A4 | |
| SCHEMBL14837630 | 0.74 | IMPDH2 (0.58) | IMPDH2IMPDH1ATMGPR84CYP3A4 | |
| SCHEMBL8161503 | 0.73 | IMPDH2 (0.56) | IMPDH2IMPDH1ATMGPR84CYP3A4 | |
| SCHEMBL5797502 | 0.71 | IMPDH2 (0.55) | IMPDH2IMPDH1MAPK1ATMGPR84 | |
| SCHEMBL13471396 | 0.71 | ALDH1A1 (0.33) | CYP3A4MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL1752696 | 0.71 | IMPDH2 (0.64) | IMPDH2IMPDH1ATMGPR84CYP3A4 | |
| SCHEMBL7237886 | 0.71 | IMPDH2 (0.64) | IMPDH2IMPDH1ATMGPR84CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377711-B2 | Cannabinoid type 1 receptor modulators | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2019-08-13 | — | — | US | disclosed |
| US-20180118681-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2018-05-03 | — | — | US | disclosed |
| EP-3186225-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | The Governing Council of the University of Toronto (CA) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016029310-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118681-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | CNR1, CNR2, GPR18 | IMPDH2 2996/4885IMPDH1 2038/4885MAPK1 1044/4885 |
| US-10377711-B2 | Cannabinoid type 1 receptor modulators | CNR1, CNR2, GPR18 | IMPDH2 2996/4885IMPDH1 2038/4885MAPK1 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.