Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14798525 | 0.85 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL18830719 | 0.84 | RAB9A (0.41) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL18830720 | 0.82 | CYP17A1 (0.44) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL14798978 | 0.78 | S1PR1 (0.38) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL27968697 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL14839655 | 0.75 | ACHE (0.49) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL13690793 | 0.75 | MEN1 (0.52) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL14798981 | 0.73 | S1PR1 (0.36) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL14805296 | 0.73 | L3MBTL1 (0.36) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL10086349 | 0.71 | SNCA (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013045280-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-04-04 | — | — | WO | disclosed |