Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 5/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | RORA | P35398 | 2/20 | 0.33 |
| ▸ | RORB | Q92753 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656350 | 0.88 | HSD11B1 (0.38) | HSD11B1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL1533291 | 0.85 | HSD11B1 (0.36) | HSD11B1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL1772470 | 0.84 | HSD11B1 (0.35) | HSD11B1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL501412 | 0.83 | HSD11B1 (0.38) | HSD11B1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL2437767 | 0.81 | HTR6 (0.38) | HSD11B1TSHRHTR6SMN1; SMN2NR1H3 | |
| SCHEMBL217002 | 0.81 | HTR6 (0.38) | HSD11B1TSHRHTR6SMN1; SMN2NR1H3 | |
| SCHEMBL962839 | 0.81 | HSD11B1 (0.41) | HSD11B1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL37033 | 0.79 | HTR6 (0.42) | HSD11B1TSHRHTR6SMN1; SMN2NR1H3 | |
| SCHEMBL965951 | 0.78 | CA1 (0.39) | HSD11B1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL51400 | 0.77 | CA1 (0.43) | HSD11B1HTR6NR1I2NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940471-B2 | Actinic-ray- or radiation-sensitive resin composition and method of forming pattern using the composition | FUJIFILM CORPORATION (JP) | 2015-01-27 | — | — | US | disclosed |
| US-20110076615-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |