SCHEMBL1484293

SCHEMBL1484293

CCCCCC(Br)CCCC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.48
LCK P06239 1/20 0.46
PPARD Q03181 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
OPRM1 P35372 1/20 0.46
LMNA P02545 1/20 0.42
ZDHHC7 Q9NXF8 1/20 0.41
TSHR P16473 2/20 0.41
THRB P10828 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CA2 P00918 1/20 0.39
FDPS P14324 4/20 0.39
GPR84 Q9NQS5 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28234661 0.97 DNM1 (0.46) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL18107274 0.97 DNM1 (0.52) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL18107273 0.97 DNM1 (0.52) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL18107347 0.97 DNM1 (0.52) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL14028946 0.97 DNM1 (0.52) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL9751616 0.97 DNM1 (0.52) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL12328082 0.97 DNM1 (0.52) DNM1LCKPPARDZDHHC20ZDHHC2
SCHEMBL7532284 0.97 LCK (0.48) DNM1LCKPPARDZDHHC20ZDHHC2
Phosphine SCHEMBL10882704 0.94 DNM1 (0.50) DNM1LCKPPARDZDHHC20ZDHHC2
Phosphine SCHEMBL19411902 0.94 DNM1 (0.50) DNM1LCKPPARDZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431630-A Biquaternary ammonium salt resin and preparation method and application thereof 南京科技职业学院 2025-02-14 CN disclosed
US-20170342031-A1 QUENCHER WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-30 US disclosed
US-9738738-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2017-08-22 US disclosed
US-20160289355-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
US-9388172-B2 Substituted carbamate compounds HOFFMANN-LA ROCHE INC. (US) 2016-07-12 US disclosed
CN-105331447-A Sterilizing cleaning composition with rich and stable foam LI BIDAN 2016-02-17 CN disclosed
EP-2917208-A1 [3-HETEROARYL-2-TRIFLUOROMETHYL-PROPYL]-PIPERIDIN-1-YLE OR -MORPHOLIN-4-YLE COMPOUNDS AS TRPA1 ANTAGONISTS FOR THE TREATMENT OF RESPIRATORY DISEASES F. Hoffmann-La Roche AG (CH) 2015-09-16 EP disclosed
US-20150239873-A1 SUBSTITUTED CARBAMATE COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2015-08-27 US disclosed
WO-2014072325-A1 [3-HETEROARYL-2-TRIFLUOROMETHYL-PROPYL]-PIPERIDIN-1-YLE OR -MORPHOLIN-4-YLE COMPOUNDS AS TRPA1 ANTAGONISTS FOR THE TREATMENT OF RESPIRATORY DISEASES F. HOFFMANN-LA ROCHE AG (CH) 2014-05-15 WO disclosed
US-8404731-B2 Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors TRANSTECH PHARMA, INC. (US) 2013-03-26 US disclosed
US-20050187277-A1 Substituted azole derivatives, compositions, and methods of use TRANSTECH PHARMA, INC. 2005-08-25 US disclosed
US-6933303-B2 Heteroaryl-fused nitrogen heterocycles as therapeutic agents TRANSTECH PHARMA, INC. (US) 2005-08-23 US disclosed
US-20050096335-A1 Heteroaryl - fused nitrogen heterocycles as therapeutic agents TRANSTECH PHARMA, INC. 2005-05-05 US disclosed
US-20040192743-A1 Substituted azole derivatives as therapeutic agents TRANSTECH PHARMA, INC. 2004-09-30 US disclosed
US-20040186151-A1 Substituted azole derivatives as therapeutic agents TRANSTECH PHARMA, INC. 2004-09-23 US disclosed
WO-2004071447-A2 SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS TRANSTECH PHARMA INC. (US) 2004-08-26 WO disclosed
WO-2004071448-A2 SUBSTITUTED AZOLE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES TRANSTECH PHARMA INC. (US) 2004-08-26 WO disclosed
EP-1438310-A1 BETA-CARBOLIN DERIVATIVES AS PTP-INHIBITORS TransTech Pharma Inc. (US) 2004-07-21 EP disclosed
US-20040014778-A1 Heteroaryl - fused nitrogen heterocycles as therapeutic agents VTVX HOLDINGS I LLC 2004-01-22 US disclosed
WO-2003033496-A1 BETA-CARBOLIN DERIVATIVES AS PTP-INHIBITORS TRANSTECH PHARMA, INC. (US) 2003-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192743-A1 Substituted azole derivatives as therapeutic agents PTPRS, PTPRO, PTPRJ DNM1 2613/4885LCK 92/4885PPARD 2359/4885
US-20040014778-A1 Heteroaryl - fused nitrogen heterocycles as therapeutic agents PTPRG, PTPRM, PTPRC DNM1 2495/4885LCK 79/4885PPARD 1845/4885
US-20050096335-A1 Heteroaryl - fused nitrogen heterocycles as therapeutic agents PTPRG, PTPRM, PTPRC DNM1 2495/4885LCK 79/4885PPARD 1845/4885
US-20150239873-A1 SUBSTITUTED CARBAMATE COMPOUNDS TRPA1, TRPV1, TRPV5 DNM1 3278/4885LCK 1336/4885PPARD 1134/4885
US-20050187277-A1 Substituted azole derivatives, compositions, and methods of use PTPRO, PTPN5, PTPRE DNM1 3272/4885LCK 97/4885PPARD 2749/4885
US-20170342031-A1 QUENCHER AHR, GFER, AKR1A1 DNM1 2437/4885LCK 4140/4885PPARD 2094/4885
US-20040186151-A1 Substituted azole derivatives as therapeutic agents PTPRS, PTPRO, PTPRJ DNM1 2613/4885LCK 92/4885PPARD 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.