Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.79 |
| ▸ | NOS1 | P29475 | 9/20 | 0.67 |
| ▸ | NOS3 | P29474 | 5/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | DDAH1 | O94760 | 6/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196828 | 1.00 | NOS2 (0.79) | NOS2NOS1NOS3CYP2C19MEN1 | |
| SCHEMBL995818 | 1.00 | NOS2 (0.79) | NOS2NOS1NOS3CYP2C19MEN1 | |
| SCHEMBL13484050 | 1.00 | NOS2 (0.79) | NOS2NOS1NOS3CYP2C19MEN1 | |
| SCHEMBL31436337 | 0.89 | NOS2 (0.68) | NOS2NOS1NOS3CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL30114268 | 0.87 | NOS2 (0.66) | NOS2NOS1NOS3CYP2C19MEN1 | |
| L-Nio SCHEMBL15944942 | 0.80 | NOS2 (1.00) | NOS2NOS1NOS3CYP2C19MEN1 | |
| Arginine SCHEMBL43261 | 0.80 | NOS2 (1.00) | NOS2NOS1NOS3CYP2C19MEN1 | |
| Arginine SCHEMBL288835 | 0.80 | NOS2 (1.00) | NOS2NOS1NOS3CYP2C19MEN1 | |
| Arginine SCHEMBL30577923 | 0.80 | NOS2 (1.00) | NOS2NOS1NOS3CYP2C19MEN1 | |
| Arginine SCHEMBL288993 | 0.80 | NOS2 (1.00) | NOS2NOS1NOS3CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3223834-B2 | PROBIOTIC AND PREBIOTIC COMPOSITIONS COMPRISING BLAUTIA SPECIES FOR REDUCING INFLAMMATION | EVELO BIOSCIENCES INC (US) | 2023-07-12 | — | — | EP | disclosed |
| US-11672834-B2 | Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome | EVELO BIOSCIENCES, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220323511-A1 | PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND METHODS OF USE THEREOF FOR MODULATION OF THE MICROBIOME | PHARMABIOME AG (CH) | 2022-10-13 | — | — | US | disclosed |
| EP-2764370-B1 | MYOSIN BINDING PROTEIN-C FOR USE IN METHODS RELATING TO DIASTOLIC HEART FAILURE | UNIV ILLINOIS (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-2764370-A2 | MYOSIN BINDING PROTEIN-C FOR USE IN METHODS RELATING TO DIASTOLIC HEART FAILURE | The Board of Trustees of the University of Illinois (US) | 2014-08-13 | — | — | EP | disclosed |
| US-20140011811-A1 | MYOSIN BINDING PROTEIN-C FOR USE IN METHODS RELATING TO DIASTOLIC HEART FAILURE | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2014-01-09 | — | — | US | disclosed |
| WO-2013052933-A2 | MYOSIN BINDING PROTEIN-C FOR USE IN METHODS RELATING TO DIASTOLIC HEART FAILURE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011811-A1 | MYOSIN BINDING PROTEIN-C FOR USE IN METHODS RELATING TO DIASTOLIC HEART FAILURE | MYOF, FABP3, MYH2 | NOS2 2969/4885NOS1 3157/4885NOS3 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.