Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 16/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178364 | 0.87 | ALDH1A1 (0.62) | NPBWR1HTTALDH1A1SMN1; SMN2PKM | |
| SCHEMBL2551062 | 0.87 | NPBWR1 (0.77) | NPBWR1MCHR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL21521858 | 0.84 | NPBWR1 (0.61) | NPBWR1MCHR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL26915060 | 0.84 | NPBWR1 (0.61) | NPBWR1MCHR1HTTALDH1A1PKM | |
| SCHEMBL20463265 | 0.83 | NPBWR1 (0.60) | NPBWR1MCHR1HTTALDH1A1 | |
| SCHEMBL14844531 | 0.82 | NPBWR1 (0.84) | NPBWR1MCHR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL27077877 | 0.82 | NPBWR1 (0.66) | NPBWR1MCHR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL26915070 | 0.81 | NPBWR1 (0.57) | NPBWR1MCHR1HTTALDH1A1PKM | |
| SCHEMBL21521851 | 0.81 | NPBWR1 (0.61) | NPBWR1MCHR1HTTALDH1A1PKM | |
| SCHEMBL27176044 | 0.81 | NPBWR1 (0.57) | NPBWR1MCHR1HTTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026086928-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2026-04-30 | — | — | WO | disclosed |
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| CN-103874688-B | Herbicidal pyridazinone derivatives | 先正达有限公司 | 2016-09-14 | — | — | CN | disclosed |
| EP-2763968-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LTD (GB) | 2016-02-24 | — | — | EP | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| EP-2763968-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | Syngenta Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050421-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | PRDX6, PRDX1, CBR3 | NPBWR1 926/4885MCHR1 1513/4885HTT 3989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.