Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844997 | 0.74 | ALDH1A1 (0.33) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL14844550 | 0.72 | ALDH1A1 (0.36) | ALDH1A1HPGDLRRK2BRD9 | |
| SCHEMBL14844488 | 0.71 | RAB9A (0.39) | ALDH1A1HPGDLRRK2NPBWR1MCHR1 | |
| SCHEMBL14844412 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDLRRK2PDE10A | |
| SCHEMBL16716777 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDNPBWR1 | |
| SCHEMBL14845056 | 0.70 | LRRK2 (0.35) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL16716787 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HPGDLRRK2PDE10ANPBWR1 | |
| SCHEMBL14844549 | 0.69 | ALDH1A1 (0.56) | ALDH1A1HPGDNPBWR1KAT2BBRD9 | |
| SCHEMBL16716785 | 0.68 | ALDH1A1 (0.37) | ALDH1A1HPGDLRRK2NPBWR1MCHR1 | |
| SCHEMBL14844564 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDNPBWR1MCHR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| EP-2763968-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LTD (GB) | 2016-02-24 | — | — | EP | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| EP-2763968-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | Syngenta Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050421-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | PRDX6, PRDX1, CBR3 | ALDH1A1 861/4885HPGD 3113/4885LRRK2 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.