Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 4/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875388 | 0.84 | TDP1 (0.50) | HTTTDP1POLBAPEX1ALDH1A1 | |
| SCHEMBL14845462 | 0.82 | HTT (0.33) | HTTTDP1POLBAPEX1PKM | |
| SCHEMBL13875440 | 0.82 | CES2 (0.49) | HTTTDP1POLBAPEX1CYP3A4 | |
| SCHEMBL13875430 | 0.81 | RAB9A (0.43) | HTTTDP1POLBAPEX1ALDH1A1 | |
| SCHEMBL13875413 | 0.76 | CA12 (0.48) | POLBCYP3A4TSHRSMN1; SMN2PRSS1 | |
| SCHEMBL1131138 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL14845436 | 0.74 | THRB (0.33) | ALDH1A1TSHRTHRBTHRA | |
| SCHEMBL15865271 | 0.73 | TDP1 (0.56) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL15865003 | 0.72 | TDP1 (0.53) | TDP1ALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL13531603 | 0.72 | ALDH1A1 (0.49) | HTTALDH1A1CYP3A4HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |