Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842968 | 0.88 | THRB (0.57) | THRBL3MBTL1ALDH1A1TSHRHPGD | |
| SCHEMBL22479358 | 0.86 | THRB (0.43) | THRBADRB2ADRB1ADRB3L3MBTL1 | |
| SCHEMBL2843821 | 0.83 | THRB (0.47) | THRBL3MBTL1ALDH1A1HPGDTHRA | |
| SCHEMBL10780166 | 0.82 | SMN1; SMN2 (0.35) | THRBADRB2ADRB1ADRB3L3MBTL1 | |
| SCHEMBL2845219 | 0.81 | CES2 (0.46) | ALDH1A1MAPTRAB9APARP10APEX1 | |
| Fluoride SCHEMBL27561287 | 0.80 | CES2 (0.44) | ALDH1A1MAPTRAB9APARP10APEX1 | |
| SCHEMBL12082533 | 0.80 | L3MBTL1 (0.54) | THRBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL12994186 | 0.79 | THRB (0.44) | THRBTHRAPPARG | |
| SCHEMBL93929 | 0.79 | THRB (0.46) | THRBALDH1A1TSHRHPGDHTT | |
| SCHEMBL10013677 | 0.78 | ALDH1A1 (0.55) | THRBL3MBTL1ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |