SCHEMBL14845463

SCHEMBL14845463

C/C=C\OOCCOC(=O)C(=O)c1ccc(CS)cc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14845473 0.83 THRB (0.34) THRATHRB
SCHEMBL14845445 0.82 THRB (0.32) THRB
SCHEMBL14845438 0.77 PKM (0.33)
SCHEMBL2121921 0.74 ALDH1A1 (0.47)
SCHEMBL13875433 0.72 CES2 (0.47)
SCHEMBL14845444 0.72 THRB (0.35) THRATHRB
SCHEMBL13875422 0.71 RAB9A (0.42)
SCHEMBL13875434 0.71 CES2 (0.46)
SCHEMBL13875442 0.71 PLK1 (0.36)
SCHEMBL14845436 0.71 THRB (0.33) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8414982-B2 Process for the production of strongly adherent coatings BASF SE (DE) 2013-04-09 US disclosed