Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 5/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.58 |
| ▸ | PTPRC | P08575 | 4/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.41 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.41 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.41 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.38 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | GSTA1 | P08263 | 5/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.33 |
| ▸ | PGK1 | P00558 | 5/20 | 0.32 |
| ▸ | PGK2 | P07205 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848443 | 0.87 | PTPRB (0.49) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14848393 | 0.85 | PTPRB (0.67) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14848402 | 0.81 | PTPRB (0.44) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14848403 | 0.81 | PTPRB (0.44) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14850434 | 0.76 | PTPRB (1.00) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL2555769 | 0.74 | SRC (0.46) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL2984001 | 0.71 | PTPRB (0.55) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL2990273 | 0.71 | PTPRB (0.55) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14848404 | 0.70 | PTPRB (0.42) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL5659750 | 0.68 | CA2 (0.48) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | KOMISARENKO SERHII VASYL OVYCH (UA) | 2013-04-11 | — | — | US | disclosed |
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | KOMISARENKO SERHII VASYL OVYCH (UA) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | FGB, F2, TFPI | PTPRB 519/4885PTPN2 1397/4885PTPN1 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.