Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 3/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 5/20 | 0.34 |
| ▸ | PGK2 | P07205 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848390 | 0.74 | PTPRB (0.58) | SRCPTPRBPTPRCPTPN2PTPN1 | |
| SCHEMBL9301497 | 0.69 | SRC (0.75) | SRCPGK1PGK2 | |
| SCHEMBL9450680 | 0.67 | SRC (0.70) | SRCPGK1PGK2 | |
| SCHEMBL2171583 | 0.64 | SRC (0.65) | SRCPGK1PGK2 | |
| SCHEMBL4094661 | 0.64 | SRC (1.00) | SRCPGK1PGK2 | |
| SCHEMBL5659750 | 0.63 | CA2 (0.48) | SRC | |
| SCHEMBL5936840 | 0.62 | SRC (0.62) | SRCPGK1PGK2 | |
| SCHEMBL13745406 | 0.61 | MMP8 (0.50) | SRCPGK1PGK2 | |
| SCHEMBL15367395 | 0.61 | SRC (0.39) | SRCPTPRBPTPRCPTPN2PTPN1 | |
| SCHEMBL744205 | 0.60 | SRC (0.60) | SRCPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | KOMISARENKO SERHII VASYL OVYCH (UA) | 2013-04-11 | — | — | US | claimed |
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | KOMISARENKO SERHII VASYL OVYCH (UA) | 2013-04-11 | — | — | US | disclosed |
| WO-2011129796-A1 | 5,11,17,23-TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR THE NA SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | ИНСТЫТУТ БИОХИМИИ ИМ. О.В.ПАЛЛАДИНА НАЦИОНАЛЬНОЙ АКАДЭМИИ НАУК УКРАИНЫ (UA) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129796-A1 | 5,11,17,23-TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR THE NA SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | ИНСТЫТУТ БИОХИМИИ ИМ. О.В.ПАЛЛАДИНА НАЦИОНАЛЬНОЙ АКАДЭМИИ НАУК УКРАИНЫ (UA) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | FGB, F2, TFPI | SRC 47/4885PTPRB 519/4885PTPRC 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.