Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.31 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.31 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848390 | 0.70 | PTPRB (0.58) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14848393 | 0.63 | PTPRB (0.67) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL25044900 | 0.62 | GABRA1 (0.46) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL14848443 | 0.61 | PTPRB (0.49) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL2990273 | 0.57 | PTPRB (0.55) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL2984001 | 0.57 | PTPRB (0.55) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL12760314 | 0.55 | PRKCG (0.38) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL17995569 | 0.54 | CD69 (0.46) | PTPRBPTPN2PTPN1PTPN11PTPRC | |
| SCHEMBL12535785 | 0.53 | CTSA (0.48) | L3MBTL1 | |
| SCHEMBL15704412 | 0.53 | CTSA (0.48) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | KOMISARENKO SERHII VASYL OVYCH (UA) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090494-A1 | TETRAKIS[BIS(DIHYDROXYPHOSPHORYL)METHYL]CALIX[4]ARENE OR ITS SODIUM SALT THEREOF AS FIBRIN POLYMERIZATION INHIBITORS | FGB, F2, TFPI | PTPRB 519/4885PTPN2 1397/4885PTPN1 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.