SCHEMBL237269

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL240803	1.00	PRKCZ (0.45)	PRKCZCYP3A4CYP2C9CYP2C19MAPK1
	SCHEMBL240802	1.00	PRKCZ (0.45)	PRKCZCYP3A4CYP2C9CYP2C19MAPK1
	SCHEMBL1982892	0.87	HSD11B1 (0.48)	CYP3A4CYP2C9CYP2C19MAPK1TSHR
	SCHEMBL1982836	0.86	PRKCZ (0.42)	PRKCZCYP3A4CYP2C9CYP2C19MAPK1
	SCHEMBL1989822	0.84	RIPK1 (0.38)	PRKCZCYP3A4CYP2C9CYP2C19MAPK1
	SCHEMBL1989823	0.84	MAPT (0.43)	PRKCZCYP3A4CYP2C19MAPK1LMNA
	SCHEMBL1989751	0.84	MAPT (0.43)	PRKCZCYP3A4CYP2C19MAPK1LMNA
	SCHEMBL2374410	0.84	RIPK1 (0.38)	PRKCZCYP3A4CYP2C9CYP2C19MAPK1
	SCHEMBL14856415	0.84	MAPT (0.43)	PRKCZCYP3A4CYP2C19MAPK1LMNA
	SCHEMBL6123402	0.84	CYP3A4 (0.41)	PRKCZCYP3A4CYP2C9CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.