Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764455 | 0.90 | BDKRB1 (0.57) | BDKRB1OPRM1OPRD1OPRK1PARP10 | |
| SCHEMBL765832 | 0.81 | BDKRB1 (0.54) | BDKRB1VNN1PARP10PARP15PARP14 | |
| SCHEMBL14856425 | 0.80 | BDKRB1 (0.48) | BDKRB1ALDH1A1KMT2ACYP3A4HTT | |
| SCHEMBL12239063 | 0.79 | BDKRB1 (0.60) | BDKRB1CYP3A4MAPK14MMP13HTT | |
| SCHEMBL184989 | 0.79 | BDKRB1 (0.50) | BDKRB1CYP3A4FAAH | |
| SCHEMBL758571 | 0.79 | BDKRB1 (0.47) | BDKRB1ALDH1A1KMT2ACYP3A4MAPK14 | |
| SCHEMBL764413 | 0.79 | BDKRB1 (0.64) | BDKRB1CYP3A4MAPK14MMP13HTT | |
| SCHEMBL185605 | 0.78 | FAAH (0.46) | BDKRB1ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL765558 | 0.78 | BDKRB1 (0.50) | BDKRB1OPRM1OPRD1OPRK1CYP3A4 | |
| SCHEMBL185085 | 0.78 | BDKRB1 (0.47) | BDKRB1ALDH1A1KMT2ACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |