Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856796 | 0.89 | TRPA1 (0.33) | TRPA1FAAHP2RX7RORCCNR2 | |
| SCHEMBL2813235 | 0.89 | OGA (0.34) | OGAAURKATRPA1P2RX7CNR2 | |
| SCHEMBL14856424 | 0.89 | P2RX7 (0.33) | AURKATRPA1FAAHP2RX7RORC | |
| SCHEMBL186462 | 0.83 | BACE1 (0.32) | TRPA1FAAHP2RX7CNR2TRPV1 | |
| SCHEMBL14856710 | 0.83 | FAAH (0.35) | TRPA1FAAHP2RX7RORCCNR2 | |
| SCHEMBL14856774 | 0.83 | FAAH (0.34) | TRPA1FAAHP2RX7TRPV1 | |
| SCHEMBL14856577 | 0.82 | FAAH (0.34) | TRPA1FAAHP2RX7CNR2TRPV1 | |
| SCHEMBL14963913 | 0.82 | HDAC3 (0.40) | AURKATRPA1P2RX7CNR2 | |
| SCHEMBL2812751 | 0.82 | P2RX7 (0.37) | AURKATRPA1P2RX7RORCCNR2 | |
| SCHEMBL14856622 | 0.81 | P2RX7 (0.32) | AURKATRPA1FAAHP2RX7CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |