SCHEMBL14857367

SCHEMBL14857367

CCCCNC(=O)CCSSc1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.53
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 3/20 0.49
ALDH1A1 P00352 4/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALOX12 P18054 1/20 0.43
ENPP2 Q13822 1/20 0.43
POLB P06746 1/20 0.42
TSHR P16473 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10051009 0.95 HPGD (0.51) HPGDSMN1; SMN2HTTALDH1A1NPC1
SCHEMBL3670854 0.95 HPGD (0.51) HPGDSMN1; SMN2HTTALDH1A1NPC1
SCHEMBL30508572 0.94 HPGD (0.50) HPGDSMN1; SMN2HTTALDH1A1NPC1
SCHEMBL13225862 0.92 HPGD (0.55) HPGDSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL29380577 0.92 HPGD (0.57) HPGDSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL155342 0.92 HPGD (0.57) HPGDSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL19444563 0.91 HPGD (0.56) HPGDSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL18519252 0.90 HPGD (0.53) HPGDSMN1; SMN2HTTALDH1A1NPC1
SCHEMBL9679353 0.89 HPGD (0.46) HPGDSMN1; SMN2HTTNPC1RAB9A
SCHEMBL20648152 0.89 HPGD (0.52) HPGDSMN1; SMN2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019755-A Nanopore 牛津纳米孔科技公开有限公司 2024-05-10 CN disclosed
CN-118011004-A Method for characterizing target polypeptides using nanopores 牛津纳米孔科技公开有限公司 2024-05-10 CN disclosed
CN-117940557-A Method for preparing modified tumor-infiltrating lymphocytes and application of modified tumor-infiltrating lymphocytes in adoptive cell therapy 艾欧凡斯生物治疗公司 2024-04-26 CN disclosed
CN-117279506-A Tumor storage and cell culture compositions 艾欧凡斯生物治疗公司 2023-12-22 CN disclosed
WO-2023018743-A1 PH-RESPONSIVE NANOPARTICLE FOR DELIVERY OF RIBONUCLEOPROTEINS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-02-16 WO disclosed
CN-115004030-A Method 牛津纳米孔科技公开有限公司 2022-09-02 CN disclosed
CN-114945679-A Method for double-strand sequencing 牛津纳米孔科技公开有限公司 2022-08-26 CN disclosed
CN-114761799-A Methods of characterizing target polypeptides using nanopores 牛津纳米孔科技公开有限公司 2022-07-15 CN disclosed
US-10675358-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-06-09 US disclosed
CN-111225958-A Conductive antifouling coating composition 哈佛大学校长及研究员协会 2020-06-02 CN disclosed
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2019-03-14 US disclosed
US-20170252453-A9 TRANSMUCOSAL DELIVERY OF PHARMACEUTICAL ACTIVE SUBSTANCES ANYGEN CO., LTD. (KR) 2017-09-07 US disclosed
US-20140256623-A1 TRANSMUCOSAL DELIVERY OF PHARMACEUTICAL ACTIVE SUBSTANCES ANYGEN CO., LTD. (KR) 2014-09-11 US disclosed
EP-2580326-A1 METHOD FOR SELECTIVE OLIGONUCLEOTIDE MODIFICATION Antisense Pharma GmbH (DE) 2013-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10675358-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A HPGD 2439/4885SMN1; SMN2 4460/4885HTT 4166/4885
US-20140256623-A1 TRANSMUCOSAL DELIVERY OF PHARMACEUTICAL ACTIVE SUBSTANCES SI, PIGS, MUC1 HPGD 1283/4885SMN1; SMN2 3280/4885HTT 3733/4885
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A HPGD 2255/4885SMN1; SMN2 4505/4885HTT 4090/4885
US-20170252453-A9 TRANSMUCOSAL DELIVERY OF PHARMACEUTICAL ACTIVE SUBSTANCES SI, PIGS, MUC1 HPGD 1283/4885SMN1; SMN2 3280/4885HTT 3733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.