Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2691175 | 0.97 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL3132603 | 0.84 | HPGD (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| Bromide SCHEMBL2691231 | 0.80 | HPGD (0.62) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5258963 | 0.78 | MAPK1 (0.60) | ALDH1A1SMN1; SMN2CYP19A1L3MBTL1MAPT | |
| SCHEMBL11620182 | 0.78 | LMNA (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL1156806 | 0.78 | JAK2 (0.53) | ALDH1A1SMN1; SMN2CYP19A1MAPTGAA | |
| SCHEMBL6200370 | 0.78 | L3MBTL1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL11146920 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| Bromide SCHEMBL8967719 | 0.77 | MAPK1 (0.59) | ALDH1A1SMN1; SMN2CYP19A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL3251439 | 0.77 | CYP19A1 (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128159-B1 | COMPOUND WHEREIN SUBSTITUTED BIPYRIDYL GROUP IS CONNECTED WITH PYRIDOINDOLE RING STRUCTURE THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2017-08-16 | — | — | EP | disclosed |
| US-9525140-B2 | Arylamine compound useful in an organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| EP-2299509-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2016-06-29 | — | — | EP | disclosed |
| CN-104617229-A | Organic electroluminescent device | HODOGAYA CHEMICAL CO LTD | 2015-05-13 | — | — | CN | disclosed |
| US-8771841-B2 | Organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20140039221-A1 | ARYLAMINE COMPOUND USEFUL IN AN ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-02-06 | — | — | US | disclosed |
| CN-103553935-A | Organic electroluminescent device | HODOGAYA CHEMICAL CO LTD | 2014-02-05 | — | — | CN | disclosed |
| EP-2677562-A2 | Arylamines for organic electroluminescent devices | Hodogaya Chemical Co., Ltd. (JP) | 2013-12-25 | — | — | EP | disclosed |
| EP-2383816-B1 | Organic electroluminescent device | HODOGAYA CHEMICAL CO LTD (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8252431-B2 | Compound wherein substituted bipyridyl group is connected with pyridoindole ring structure through phenylene group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| EP-2383816-A1 | Organic electroluminescent device | Hodogaya Chemical Co., Ltd. (JP) | 2011-11-02 | — | — | EP | disclosed |
| CN-102027613-A | Organic electroluminescent device | HODOGAYA CHEMICAL CO LTD | 2011-04-20 | — | — | CN | disclosed |
| US-20110073852-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-03-31 | — | — | US | disclosed |
| EP-2299509-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20100123388-A1 | COMPOUND WHEREIN SUBSTITUTED BIPYRIDYL GROUP IS CONNECTED WITH PYRIDOINDOLE RING STRUCTURE THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-05-20 | — | — | US | disclosed |
| EP-2128159-A1 | COMPOUND WHEREIN SUBSTITUTED BIPYRIDYL GROUP IS CONNECTED WITH PYRIDOINDOLE RING STRUCTURE THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100123388-A1 | COMPOUND WHEREIN SUBSTITUTED BIPYRIDYL GROUP IS CONNECTED WITH PYRIDOINDOLE RING STRUCTURE THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | SLCO4C1, PNPO, EPHA1 | ALDH1A1 400/4885KDM4E 1051/4885HPGD 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.