SCHEMBL1485973

SCHEMBL1485973

O=S(=O)(O)c1cc(O)c2ccc(-n3nc4ccc5c(S(=O)(=O)O)cc(S(=O)(=O)O)cc5c4n3)cc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.44
NSD2 O96028 3/20 0.44
PTPN11 Q06124 3/20 0.44
DUSP3 P51452 2/20 0.44
PTPN5 P54829 2/20 0.44
PRMT1 Q99873 2/20 0.42
NT5E P21589 3/20 0.39
CTDSP1 Q9GZU7 1/20 0.36
ALDH1A1 P00352 4/20 0.35
CYP2C9 P11712 3/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP2C19 P33261 1/20 0.35
CASP7 P55210 1/20 0.35
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTPRC P08575 1/20 0.31
ALOX15 P16050 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12157599 0.90 ALOX5 (0.34) CASP6NSD2PTPN11DUSP3PTPN5
SCHEMBL12174293 0.90 CASP6 (0.47) CASP6NSD2PTPN11DUSP3PTPN5
SCHEMBL11911520 0.88 PTPN11 (0.35) CASP6NSD2PTPN11DUSP3PTPN5
SCHEMBL4598355 0.82 CASP6 (0.36) CASP6NSD2PTPN11DUSP3PTPN5
SCHEMBL11913141 0.82 NPC1 (0.38) CASP6NSD2PTPN11DUSP3PTPN5
SCHEMBL11374899 0.82 MAPT (0.40) ALDH1A1CYP2C9HSD17B10CASP7MEN1
SCHEMBL11913038 0.81 CD40 (0.43) PRMT1CYP2C9MEN1THRBKMT2A
SCHEMBL12157604 0.81 CYP2C9 (0.41) CASP6NSD2PTPN11DUSP3PTPN5
SCHEMBL19235018 0.81 CD40 (0.47) PRMT1ALDH1A1CYP2C9MEN1THRB
SCHEMBL19085485 0.80 SENP3 (0.36) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 WO disclosed
US-9354371-B2 Azo compounds, and dye-based polarizing films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-31 US disclosed
US-9341746-B2 Azo compound, dye-based polarizing film and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160109619-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate POLATECHNO CO LTD (JP) 2016-04-21 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed
US-20150331148-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate NIPPON KAYAKU KK (JP) 2015-11-19 US disclosed
US-20140218628-A1 Polarizer And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed
US-8477268-B2 Azo compound and salts thereof, as well as dye-based polarization films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-07-02 US disclosed
US-8389124-B2 Azo compound and dye polarizing film containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-05 US disclosed
US-8389122-B2 Azo compound and dye polarizing film containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-05 US disclosed
US-8232375-B2 Azo compound, and dye-containing polarizing film comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-07-31 US disclosed
US-20110267691-A1 Azo Compound And Dye Polarizing Film Containing The Same POLATECHNO CO., LTD. (JP) 2011-11-03 US disclosed
US-20110164208-A1 Azo Compound And Salts Thereof, As Well As Dye-Based Polarization Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 US disclosed
US-20110075076-A1 Azo Compounds, And Dye-Based Polarizing Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-31 US disclosed
US-20100226008-A1 Azo Compound, And Dye-Containing Polarizing Film Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-09-09 US disclosed
US-20090174942-A1 Azo compound and dye polarizing film containing the same POLATECHNO CO., LTD. (JP) 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100226008-A1 Azo Compound, And Dye-Containing Polarizing Film Comprising The Same RCC1, IK, NAP1L1 CASP6 2863/4885NSD2 1691/4885PTPN11 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.