SCHEMBL19085485

SCHEMBL19085485

O=S(=O)(O)c1cc(S(=O)(=O)O)c2ccc3nn(-c4ccc(/C=C/c5ccc(/C=C/c6ccc(-n7nc8ccc9c(S(=O)(=O)O)cc(S(=O)(=O)O)cc9c8n7)cc6S(=O)(=O)O)cc5)c(S(=O)(=O)O)c4)nc3c2c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SENP3 Q9H4L4 2/20 0.36
SENP2 Q9HC62 2/20 0.36
SENP1 Q9P0U3 2/20 0.36
SUMO2 P61956 1/20 0.36
SUMO1 P63165 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
RAD1 O60671 1/20 0.32
P2RY6 Q15077 1/20 0.32
ENPP2 Q13822 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14411295 0.95 SENP3 (0.35) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL4598355 0.84 CASP6 (0.36) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL17565781 0.82 SENP2 (0.40) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL10793745 0.82 KDM4E (0.36) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL10789824 0.81 KDM4E (0.35) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL11913141 0.81 NPC1 (0.38) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL17565780 0.81 TTR (0.38) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL11374899 0.81 MAPT (0.40)
SCHEMBL31315043 0.80 ALOX5 (0.46) SENP3SENP2SENP1SUMO2SUMO1
SCHEMBL8746480 0.80 ALOX5 (0.46) SENP3SENP2SENP1SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2019-01-17 US disclosed
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL HNRNPM, NPM1, HNRNPF SENP3 2357/4885SENP2 3083/4885SENP1 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.