Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 12/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15827151 | 1.00 | MAP3K5 (0.79) | MAP3K5MEN1PKMKMT2AMCL1 | |
| SCHEMBL14860012 | 1.00 | MAP3K5 (0.79) | MAP3K5MEN1PKMKMT2AMCL1 | |
| SCHEMBL6784938 | 0.96 | MEN1 (0.82) | MAP3K5MEN1PKMKMT2AMCL1 | |
| SCHEMBL3903277 | 0.94 | HIF1AN (0.80) | MAP3K5MEN1PKMKMT2AMCL1 | |
| SCHEMBL3903272 | 0.94 | HIF1AN (0.80) | MAP3K5MEN1PKMKMT2AMCL1 | |
| SCHEMBL21079119 | 0.90 | MEN1 (0.93) | MAP3K5MEN1PKMKMT2AMCL1 | |
| SCHEMBL3904248 | 0.89 | MAPT (0.77) | MAP3K5MEN1KMT2AMCL1TDP1 | |
| SCHEMBL3905933 | 0.89 | MAPT (0.77) | MAP3K5MEN1KMT2AMCL1TDP1 | |
| SCHEMBL7859580 | 0.89 | MAPT (0.77) | MAP3K5MEN1KMT2AMCL1TDP1 | |
| SCHEMBL26458799 | 0.86 | MEN1 (1.00) | MAP3K5MEN1PKMKMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228548-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | AVIXGEN INC. (KR) | 2021-07-29 | — | — | US | claimed |
| EP-3827827-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | Avixgen Inc. (KR) | 2021-06-02 | — | — | EP | claimed |
| WO-2020022789-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | (주) 에빅스젠 | 2020-01-30 | — | — | WO | claimed |
| EP-2583969-A2 | NOVEL RHODANINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF AIDS CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENTS | Avixgen Inc. (KR) | 2013-04-24 | — | — | EP | claimed |
| US-20130096125-A1 | NOVEL RHODANINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PAHRMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF AIDS CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENTS | AVIXGEN INC. (KR) | 2013-04-18 | — | — | US | claimed |
| US-20210228548-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | AVIXGEN INC. (KR) | 2021-07-29 | — | — | US | disclosed |
| EP-3827827-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | Avixgen Inc. (KR) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020022789-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | (주) 에빅스젠 | 2020-01-30 | — | — | WO | disclosed |
| US-8759536-B2 | Rhodanine derivatives, method for preparing same, and pharmaceutical composition for the prevention or treatment of aids containing the rhodanine derivatives as active ingredients | AVIXGEN INC. (KR) | 2014-06-24 | — | — | US | disclosed |
| EP-2583969-A2 | NOVEL RHODANINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF AIDS CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENTS | Avixgen Inc. (KR) | 2013-04-24 | — | — | EP | disclosed |
| US-20130096125-A1 | NOVEL RHODANINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PAHRMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF AIDS CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENTS | AVIXGEN INC. (KR) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096125-A1 | NOVEL RHODANINE DERIVATIVES, METHOD FOR PREPARING SAME, AND PAHRMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF AIDS CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENTS | LRAT, MRM1, ADH7 | MAP3K5 3482/4885MEN1 2209/4885PKM 327/4885 |
| US-20210228548-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OSTEOARTHRITIS, CONTAINING RHODANINE DERIVATIVE AS ACTIVE INGREDIENT | COL2A1, COL1A1, SYVN1 | MAP3K5 3896/4885MEN1 4074/4885PKM 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.