Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068898 | 0.78 | HPGD (0.68) | HPGDALDH1A1HTTRAB9ANAMPT | |
| SCHEMBL13753673 | 0.77 | HPGD (0.68) | HPGDALDH1A1HTTRAB9ANAMPT | |
| SCHEMBL12893239 | 0.77 | HPGD (0.68) | HPGDHTTMEN1KMT2APLK1 | |
| SCHEMBL12418676 | 0.77 | PLK1 (0.49) | HPGDALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL15489278 | 0.76 | HPGD (0.66) | HPGDALDH1A1HTTRAB9ANAMPT | |
| SCHEMBL12680144 | 0.76 | ALDH1A1 (0.71) | HPGDALDH1A1RAB9AKMT2AKDM4E | |
| SCHEMBL13753672 | 0.75 | HPGD (0.65) | HPGDALDH1A1HTTRAB9ANAMPT | |
| SCHEMBL3033950 | 0.75 | HPGD (0.64) | HPGDALDH1A1HTTRAB9ANAMPT | |
| SCHEMBL13225445 | 0.74 | PLK1 (0.46) | HPGDALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL12417397 | 0.74 | MAPT (0.51) | ALDH1A1RAB9AMAPTPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420068-B2 | Polymer-based compositions and conjugates of antimicrobial agents | NEKTAR THERAPEUTICS (US) | 2013-04-16 | — | — | US | disclosed |