Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COL1A1 | P02452 | 12/20 | 0.53 |
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15133348 | 0.88 | COL1A1 (0.64) | COL1A1PARP1 | |
| Matrinic Acid SCHEMBL15134531 | 0.71 | COL1A1 (0.35) | COL1A1 | |
| Matrinic Acid SCHEMBL14865317 | 0.71 | COL1A1 (0.35) | COL1A1 | |
| SCHEMBL26727341 | 0.61 | SMN1; SMN2 (0.46) | ACEREN | |
| SCHEMBL7227535 | 0.59 | ITGB3 (0.55) | — | |
| SCHEMBL12192533 | 0.59 | ATM (0.33) | — | |
| SCHEMBL22267901 | 0.59 | CYP1A2 (0.44) | — | |
| SCHEMBL12192539 | 0.59 | ATM (0.33) | — | |
| SCHEMBL9391353 | 0.59 | CYP1A2 (0.40) | ACEREN | |
| SCHEMBL26208344 | 0.58 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190345-A1 | MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | CSPC Zongqi Pharmaceutical Technology (Shijiahuang) Co., Ltd. (CN) | 2013-07-25 | — | — | US | disclosed |
| US-20130190345-A1 | MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | CSPC Zongqi Pharmaceutical Technology (Shijiahuang) Co., Ltd. (CN) | 2013-07-25 | — | — | US | disclosed |
| EP-2581376-A1 | MATRINIC ACID/ MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2013-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190345-A1 | MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | MATR3, MMP7, MAT1A | COL1A1 87/4885PARP1 2233/4885ACE 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.