SCHEMBL14865675

SCHEMBL14865675

C=C1OC(=O)c2cc(C(C)c3ccc4c(c3)C(=O)OC4=O)ccc21

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NR1H3 Q13133 1/20 0.33
LMNA P02545 1/20 0.32
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433935 0.89 ALDH1A1 (0.48) ALDH1A1ALOX15TDP1LMNAELANE
SCHEMBL14865631 0.83 ALOX15 (0.38) ALDH1A1ALOX15TDP1
SCHEMBL15511869 0.83 TDP1 (0.45) ALDH1A1ALOX15TDP1LMNA
SCHEMBL18024822 0.83 LMNA (0.46) ALDH1A1ALOX15TDP1NR1H3LMNA
SCHEMBL10328403 0.79 UGT2B7 (0.46) ALDH1A1ALOX15TDP1LMNA
SCHEMBL11436231 0.78 LMNA (0.52) ALDH1A1ALOX15TDP1NR1H3LMNA
SCHEMBL13907658 0.77 TDP1 (0.44) ALDH1A1ALOX15TDP1LMNA
Benzene SCHEMBL4958274 0.77 LMNA (0.50) ALDH1A1ALOX15TDP1NR1H3LMNA
SCHEMBL9718941 0.75 ALOX15 (0.43) ALDH1A1ALOX15TDP1LMNA
SCHEMBL12861135 0.74 ELANE (0.50) ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 US disclosed