SCHEMBL10328403

SCHEMBL10328403

CC(O)c1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.46
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NOX1 Q9Y5S8 1/20 0.36
LMNA P02545 1/20 0.35
BCL2 P10415 1/20 0.35
MCL1 Q07820 1/20 0.35
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35
CA7 P43166 3/20 0.35
CA4 P22748 2/20 0.35
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
CREBBP Q92793 1/20 0.34
STAT3 P40763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11436231 0.84 LMNA (0.52) ALOX15TDP1ALDH1A1LMNABCL2
SCHEMBL22017376 0.84 ALOX15 (0.46) ALOX15TDP1ALDH1A1MCL1CA12
SCHEMBL433935 0.84 ALDH1A1 (0.48) ALOX15TDP1ALDH1A1LMNACA12
SCHEMBL9405094 0.84 ALOX15 (0.46) ALOX15TDP1ALDH1A1CA12CA1
Benzene SCHEMBL4958274 0.82 LMNA (0.50) ALOX15TDP1ALDH1A1LMNABCL2
SCHEMBL9718941 0.81 ALOX15 (0.43) ALOX15TDP1ALDH1A1LMNACA12
SCHEMBL14865631 0.79 ALOX15 (0.38) ALOX15TDP1ALDH1A1CA12CA1
SCHEMBL14865675 0.79 ALDH1A1 (0.41) ALOX15TDP1ALDH1A1LMNA
SCHEMBL2398331 0.78 BCL2 (0.57) UGT2B7TDP1ALDH1A1MEN1KMT2A
SCHEMBL21177274 0.78 CYP3A4 (0.40) ALOX15TDP1ALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278256-B2 Fluorinated lubricants SOLVAY SOLEXIS S.P.A. (IT) 2012-10-02 US disclosed
US-8217119-B2 Additives for halopolymers SOLVAY SOLEXIS S.P.A. (IT) 2012-07-10 US disclosed
US-20100069275-A1 Fluorinated lubricants SOLVAY SOLEXIS S.P.A. (IT) 2010-03-18 US disclosed
US-20090326154-A1 Additives for Halopolymers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-31 US disclosed
US-7629483-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-08 US disclosed
US-20080194881-A1 Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives SOLVAY SOLEXIS S.P.A. (IT) 2008-08-14 US disclosed
US-7371900-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-05-13 US disclosed
US-7365229-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194881-A1 Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives FOXO1, FOXM1, F12 UGT2B7 4408/4885ALOX15 1423/4885TDP1 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.