Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433935 | 0.84 | ALDH1A1 (0.48) | ALOX15TDP1ALDH1A1LMNATYMS | |
| SCHEMBL11436231 | 0.84 | LMNA (0.52) | ALOX15TDP1ALDH1A1LMNACA1 | |
| Benzene SCHEMBL4958274 | 0.82 | LMNA (0.50) | ALOX15TDP1ALDH1A1LMNACA12 | |
| SCHEMBL10328403 | 0.81 | UGT2B7 (0.46) | ALOX15TDP1ALDH1A1LMNACA12 | |
| SCHEMBL13397789 | 0.78 | HDAC4 (0.47) | ALOX15TDP1ALDH1A1LMNA | |
| SCHEMBL15511869 | 0.78 | TDP1 (0.45) | ALOX15TDP1ALDH1A1LMNACA12 | |
| SCHEMBL22017376 | 0.76 | ALOX15 (0.46) | ALOX15TDP1ALDH1A1TYMSCA12 | |
| SCHEMBL9405094 | 0.76 | ALOX15 (0.46) | ALOX15TDP1ALDH1A1TYMSCA12 | |
| SCHEMBL28074442 | 0.76 | ALOX15 (0.46) | ALOX15TDP1ALDH1A1TYMSCA12 | |
| SCHEMBL14865675 | 0.75 | ALDH1A1 (0.41) | ALOX15TDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112926-A | Improved hardness, toughness and drilling properties | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1992-05-12 | — | — | US | disclosed |