Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14872744 | 0.86 | MEN1 (0.52) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL12244095 | 0.84 | ACHE (0.58) | ALDH1A1KDM4EFAAH | |
| SCHEMBL14859635 | 0.83 | KMT2A (0.54) | MEN1KMT2AALDH1A1KDM4EFAAH | |
| SCHEMBL1046370 | 0.82 | TSHR (0.84) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL14859632 | 0.81 | HRH3 (0.64) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL12222589 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1RAB9ATP53 | |
| SCHEMBL14872732 | 0.81 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL14860046 | 0.79 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1044760 | 0.78 | RAB9A (0.91) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL15560514 | 0.77 | KMT2A (0.54) | MEN1KMT2AALDH1A1KDM4EFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-08-20 | — | — | US | disclosed |
| US-8916705-B2 | Procaspase-activating compounds and compositions | The Board of Trustees of The University of Illilnois (US) | 2014-12-23 | — | — | US | disclosed |
| US-20130096133-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND COMPOSITIONS | The Board of Trustees of the University lllinois (US) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | CASP3, CASP5, CASP6 | MEN1 3281/4885KMT2A 3185/4885ALDH1A1 3075/4885 |
| US-20130096133-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND COMPOSITIONS | CASP3, CASP5, CASP6 | MEN1 2731/4885KMT2A 3351/4885ALDH1A1 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.