Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397026 | 0.93 | TAS1R3 (0.38) | MAPTALDH1A1IKBKBTAS1R3TAS1R1 | |
| SCHEMBL16712268 | 0.89 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1NPC1HSD17B10 | |
| SCHEMBL1115268 | 0.83 | TAS1R3 (0.39) | KDM4EALDH1A1NPSR1HSD17B10TAS1R3 | |
| SCHEMBL679235 | 0.82 | GRM6 (0.37) | MAPTKDM4EALDH1A1NPSR1NPC1 | |
| SCHEMBL15226183 | 0.81 | TAS1R3 (0.37) | MAPTKDM4EALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL16712289 | 0.80 | TAS1R3 (0.36) | MAPTNPC1IKBKBTAS1R3TAS1R1 | |
| SCHEMBL1397124 | 0.80 | GRM6 (0.37) | MAPTKDM4EALDH1A1NPSR1NPC1 | |
| SCHEMBL16712267 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1HTTHSD17B10TAS1R3 | |
| SCHEMBL1397051 | 0.79 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1NPC1HSD17B10 | |
| SCHEMBL1396996 | 0.79 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426591-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-04-23 | — | — | US | disclosed |