Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712286 | 0.91 | MEP1B (0.37) | TAS1R3TAS1R1MEP1BSCN9AKMT2A | |
| SCHEMBL16712292 | 0.84 | MEP1B (0.38) | TAS1R3TAS1R1MEP1BSCN9A | |
| SCHEMBL1397026 | 0.83 | TAS1R3 (0.38) | TAS1R3TAS1R1MEP1BIKBKBMAPT | |
| SCHEMBL16712268 | 0.82 | ALDH1A1 (0.38) | TAS1R3TAS1R1MEP1BIKBKBMAPT | |
| SCHEMBL17745513 | 0.81 | DHPS (0.38) | TAS1R3TAS1R1MEP1BSCN9A | |
| SCHEMBL14878304 | 0.80 | MAPT (0.38) | TAS1R3TAS1R1MEP1BIKBKBMAPT | |
| SCHEMBL2596682 | 0.78 | MEP1B (0.36) | TAS1R3TAS1R1MEP1BSCN9A | |
| SCHEMBL1396996 | 0.78 | ALDH1A1 (0.38) | TAS1R3TAS1R1MEP1BMAPTNPC1 | |
| SCHEMBL17745506 | 0.76 | MEP1B (0.35) | TAS1R3TAS1R1MEP1BSCN9A | |
| SCHEMBL1115268 | 0.75 | TAS1R3 (0.39) | TAS1R3TAS1R1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279178-B1 | 2-(substituted phenyl)-6-hydroxy- or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-05-20 | — | — | EP | claimed |