Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712267 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10KMOTAS1R3 | |
| SCHEMBL1397026 | 0.90 | TAS1R3 (0.38) | ALDH1A1TAS1R3TAS1R1IKBKBMEP1B | |
| SCHEMBL1397051 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10KMOTAS1R3 | |
| SCHEMBL14878304 | 0.89 | MAPT (0.38) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL1397102 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10KMOTAS1R3 | |
| SCHEMBL119198 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10KMOTAS1R3 | |
| SCHEMBL16712293 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10KMOTAS1R3 | |
| SCHEMBL16712289 | 0.82 | TAS1R3 (0.36) | TAS1R3TAS1R1IKBKBMEP1BMEN1 | |
| SCHEMBL1396996 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL1397100 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10KMOTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279178-B1 | 2-(substituted phenyl)-6-hydroxy- or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-05-20 | — | — | EP | claimed |