Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439935 | 0.89 | APP (0.64) | APPFBP1MAPTALDH1A1NPC1 | |
| SCHEMBL3365228 | 0.88 | MAOA (0.68) | HSPB1MAOAMAOBPOLBAPP | |
| SCHEMBL3365225 | 0.88 | MAOA (0.68) | HSPB1MAOAMAOBPOLBAPP | |
| SCHEMBL536 | 0.87 | HSPB1 (0.75) | HSPB1MAOAMAOBPOLBMAPT | |
| SCHEMBL7026994 | 0.87 | HSPB1 (0.75) | HSPB1MAOAMAOBPOLBMAPT | |
| Fluoride SCHEMBL4551986 | 0.84 | HSPB1 (0.72) | HSPB1MAOAMAOBPOLBMAPT | |
| Water SCHEMBL28147677 | 0.84 | HSPB1 (0.72) | HSPB1MAOAMAOBPOLBMAPT | |
| Fluoride SCHEMBL4551988 | 0.84 | HSPB1 (0.72) | HSPB1MAOAMAOBPOLBMAPT | |
| SCHEMBL28001935 | 0.84 | HSPB1 (0.72) | HSPB1MAOAMAOBPOLBMAPT | |
| Formaldehyde SCHEMBL28237406 | 0.82 | HSPB1 (0.69) | HSPB1MAOAMAOBPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |