Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3419537 | 0.87 | ALOX12 (0.36) | ADRB1LMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL3435271 | 0.75 | TDP1 (0.35) | LMNACYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL6161536 | 0.72 | SIGMAR1 (0.45) | ADRB1HTR7HTR1AHTR3ACYP2D6 | |
| SCHEMBL7129100 | 0.69 | TDP2 (0.30) | ALDH1A1PKM | |
| O-Xylene SCHEMBL28078166 | 0.69 | ADRB1 (0.59) | ADRB1HTR7LMNAHTR1AHTR3A | |
| SCHEMBL336283 | 0.67 | ADRB1 (0.63) | ADRB1HTR7HTR1AHTR3ACYP1A2 | |
| SCHEMBL1726840 | 0.66 | CYP2A6 (0.45) | CYP1A2ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6739727 | 0.66 | ADRB1 (0.61) | ADRB1HTR7LMNAHTR1AHTR3A | |
| SCHEMBL30012631 | 0.64 | SIGMAR1 (0.45) | ADRB1HTR7HTR1AHTR3AHTR2A | |
| SCHEMBL5352749 | 0.63 | ALDH1A1 (0.67) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768837-A1 | NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS | PERSTORP AB (SE) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013058690-A1 | NOVEL TETRAOXASPIRO[5.5]UNDECANE BASED PHOSPHATE COMPOUNDS AND THEIR USE AS FLAME RETARDANTS | PERSTORP AB (SE) | 2013-04-25 | — | — | WO | disclosed |