Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033801 | 0.80 | PYCR1 (0.79) | PYCR1ALDH1A1TSHRACHEUSP2 | |
| SCHEMBL4141280 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL10126418 | 0.72 | CA1 (0.51) | PYCR1ALDH1A1TSHRTP53KMT2A | |
| SCHEMBL3239026 | 0.70 | ALDH1A1 (0.56) | ALDH1A1ALDH2MEP1BTSHRTP53 | |
| SCHEMBL31747387 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL17758158 | 0.69 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL24835255 | 0.69 | CA12 (0.48) | PYCR1ALDH1A1ALDH2ACHEKMT2A | |
| SCHEMBL65825 | 0.69 | ALDH1A1 (0.59) | ALDH1A1ALDH2MEP1BTSHRTP53 | |
| Terephthalic Acid SCHEMBL3806690 | 0.68 | ALDH1A1 (0.58) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL11809995 | 0.67 | MEP1B (0.61) | ALDH1A1MEP1BTSHRTAS2R14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130101516-A1 | NANOPARTICLES AND NANOPARTICLE COMPOSITIONS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130101516-A1 | NANOPARTICLES AND NANOPARTICLE COMPOSITIONS | MCM6, MPI, MSH2 | PYCR1 4168/4885ALDH1A1 4674/4885ALDH2 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.